Windows upgrade failed (Error 0x8007042B-0x2000D) when upgrading to build 1607

So, I'm currently running the RTM build of Windows 10 Enterprise x64 and I downloaded en_windows_10_enterprise_version_1607_updated_jul_2016_x64_dvd_9054264.iso and mounted the ISO on Windows as a virtual CD. I double clicked the setup.exe to begin the installation, but, upon reboot and log in, I saw an error message popping up.

We couldn't install Windows 10
We've set your PC back to the way it was right before you started installing Windows 10.
0x8007042B - 0x2000D
The installation failed in the SAFE_OS phase with an error during MIGRATE_DATA operation

So, this means I have to clean install Windows 10 build 1607 if I ever wanted the upgrade? Is there a way to fix it?

This question probably got "solved" by a clean install, but as I had a similar Problem with a PC originally migrated from windows 7 and now put into a new domain. After testeing all other tips on the internet (Deleteing folders, turning off anti-virus-software, etc.), this tip solved it:

https://superuser.com/a/1494812/81175

The problem was in deed the orphaned profiles in the registry.