Failed to acquire the VirtualBox COM object.
The application will now terminate.
Callee RC: NS_ERROR_ABORT (0x80004004)
I tried from 5.1.10 to 5.1.22, but got the same error above.
resolved by uninstall it first and install again. NOT install it by overwite.
Solved!
Ran this as administrator:
cd /tmp
sudo rm -rf .vbox-<your user>-ipc
What worked for me was to run the uninstaller tool provided with an earlier version (4.3.14 or something) of VirtualBox.
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