Visual Studio - cannot run any projects: application was unable to start correctly (0xc0000142)

• Windows 10 x64
• Visual Studio 2012 x32
• .NET Framework 3.5 and 4.6

I cannot run/debug/F5 any projects in Visual Studio. I have tried nopCommerce, BlogEngineDotNet, File->New Website, etc. First I was getting an error about .NET 4.5 and .NET 4.0 not being registered, but I installed the fix from Microsoft (https://support.microsoft.com/en-us/kb/3002339) which resolved that issue.

Now, everytime I try to F5 I get the error below.

I've searched until I was ready to beat my head against the desk. I found a lot of posts from a few years ago saying to use dependency walker to see if any pre reqs fail, but dependency walker says its only good up to Windows 8.