IIS 7.0 error HTTP Error 500.19 -Internal Server Error (Error Code 0x80070003)

I have got IIS7 running on my Windows 2008 Server It works perfectly working for the sites and the folder that I hosted before. Now I am trying to host a folder which contains two subfolder(the subfolders contain some images).

I have correctly set the IIS_IUSRS permissions on the site folder. When I try to browse the folder I got the following error,

HTTP Error 500.19 -Internal Server Error The requested page cannot be accessed because the related configuration data for the page is invalid

Module: CustomErrorModule Notification: SendResponse Handler: Not yet determined ErrorCode: 0x80070003 ConfigError: Cannot read configurationFile ConfigFile: \? \H:\EMRImages\web.config RequestedURL: https://localhost:443/EMRMachineIamge PhysicalPath:H:\EMRImages LogonMethod: Not yet determind Logonuser:Not yet determind

** the same thing is working fine in previously host folder in the same IIS 7.0.Please help me,thanks in advance

I have had a very similar error. The line:

\\?\H:\EMRImages\web.config 

typically implies you've configured IIS to try and serve a website over mapped network drive (the \\?\ is the giveaway), this happened to me because my profile maps the drive on W:, although it was native to the machine on E:. As soon as I corrected the drive error, everything was working correctly.

0x80070003 does seem to be specifically related to this network drive issue, although I believe this Microsoft KB Article goes into some detail on it: http://support.microsoft.com/kb/207671